CMC Eye Drops Manufacturer in India | Lubricant | Artificial Tears

What We Manufacture

About CMC (Sodium Carboxymethylcellulose) Eye Drops — 9M India

9M India manufactures Sodium Carboxymethylcellulose (CMC) lubricant eye drops in 0.5% and 0.1% w/v strengths at its WHO-GMP certified sterile ophthalmic facility in Birkoni, Chhattisgarh. CMC eye drops are the most widely used artificial tear and tear substitute formulation globally — providing symptomatic relief from dry eye disease (keratoconjunctivitis sicca). Dry eye is among the most prevalent ophthalmic conditions worldwide with significantly elevated rates in the Middle East, North Africa and South Asia — 9M India’s primary export markets — due to hot, dry climatic conditions, widespread air conditioning use, increasing screen time and contact lens adoption. Studies show dry eye prevalence of 30-50% in some Middle Eastern populations, creating year-round high-volume demand for lubricant eye drops.

Formulation specifications

Specification	Details
Molecule	Sodium Carboxymethylcellulose (CMC)
Available Concentrations	0.5% w/v (moderate-severe dry eye) · 0.1% w/v (mild dry eye, frequent daytime use)
Dosage Form	Sterile Ophthalmic Solution — Lubricant / Tear Substitute
Therapeutic Class	Lubricant / Tear Substitute — Ocular Surface Disease
Pack Options	10ml and 15ml sterile multi-dose bottles
Preservative	Preserved multi-dose and preservative-free unit-dose formats available
pH Range	6.5 – 7.5 (physiological)
Osmolality	Isotonic — 285–305 mOsmol/kg
Storage	Store below 25°C, protect from light
Shelf Life	24 months
MOQ	As per enquiry — contact us

Sterile ophthalmic manufacturing at 9M India

All eye drops manufactured by 9M India are produced in classified cleanroom environments with aseptic fill-finish processes. Key manufacturing standards for CMC (Sodium Carboxymethylcellulose) Eye Drops include:

ISO-classified cleanroom — Grade A/B fill-finish zones
Water for Injection (WFI) manufactured on-site
2 micron sterile filtration for every batch
Sterility testing — compendial method, every batch
Particulate matter analysis — USP <788> / BP compliance
pH, osmolality, assay and preservative content testing
Stability studies — ICH Zone IVb (30°C / 75% RH)

Therapeutic use & clinical indications

Sodium CMC is a cellulose-derived polymer that provides a gel-like viscosity stabilising the tear film and forming a mucoadhesive protective layer on the ocular surface. CMC provides sustained lubrication, reduces friction between the eyelid and cornea, and supports corneal epithelial healing in dry eye conditions. Its mucoadhesive properties improve ocular surface retention compared to simple saline solutions.

Primary Indications:

Dry eye disease — keratoconjunctivitis sicca (KCS) — mild, moderate and severe
Ocular surface dryness from environmental irritants — air conditioning, wind, dust
Screen-related dry eye — computer vision syndrome
Contact lens-associated dryness and discomfort
Post-refractive surgery dryness — LASIK, PRK
Sjögren’s syndrome associated dry eye
Post-cataract surgery ocular surface support

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Who We Supply

Export markets & regulatory readiness

9M India exports CMC lubricant eye drops to 15+ countries across Phase 1 markets including the UAE, Iraq, Egypt, Kazakhstan, Sri Lanka and others in the Middle East, CIS, Africa and ASEAN. Dry eye prevalence is highest in our primary export markets and lubricant eye drops represent one of the highest-volume ophthalmic categories in both retail and institutional channels in these regions.

WHO-GMP Certificate
DCGI Manufacturing Licence
Certificate of Pharmaceutical Product (CoPP)
Certificate of Analysis (CoA) — sterility, particulate matter, pH, assay — batch-wise
CTD / ACTD Dossier — on request
Stability Data — ICH Zone IVb (30°C/75% RH)

Partner with 9M India for CMC (Sodium Carboxymethylcellulose) Eye Drops supply

Whether you are sourcing CMC lubricant eye drops for dry eye management programmes, institutional ophthalmic supply or export distribution — 9M India delivers WHO-GMP certified sterile manufacturing with complete documentation and reliable supply at scale.

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WHO-GMP
Certified Facility
In-House QC
Contract &
3PM Available
DCGI
Approved

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Frequently asked questions — CMC (Sodium Carboxymethylcellulose) Eye Drops

Find answers to the most common questions about our products, services, pricing, and policies.

01

Yes. 9M India manufactures Sodium Carboxymethylcellulose (CMC) lubricant eye drops in 0.5% and 0.1% w/v strengths at its WHO-GMP certified sterile ophthalmic facility in Birkoni, Chhattisgarh. All batches are manufactured under classified cleanroom conditions with aseptic fill-finish, sterility testing and full batch documentation.
02

CMC 0.5% provides higher viscosity and more sustained lubrication — preferred for moderate to severe dry eye, nocturnal use and patients requiring longer relief between doses. CMC 0.1% is a lower viscosity formulation for mild dry eye and frequent daytime use where minimal visual blur after instillation is important. 9M India manufactures both concentrations for full formulary coverage.
03

Yes. CMC lubricant drops can be used alongside most ophthalmic formulations. A minimum 5-minute interval between instillation of each formulation is recommended. CMC is typically instilled last in a multi-drop regimen. Patients on preserved eye drops often use CMC to counteract preservative-related ocular surface effects.
04

Yes. Dry eye prevalence is significantly elevated in the Middle East, North Africa and South Asia — 9M India's primary export markets — due to hot and dry climate, widespread air conditioning, high screen time and increasing contact lens use. Studies show 30-50% dry eye prevalence in some Middle Eastern populations, creating substantial year-round demand for lubricant eye drops.
05

CMC eye drops are available in 10ml and 15ml sterile multi-dose bottles. Unit-dose preservative-free vials can be considered for markets where preservative-free delivery is preferred. Private label packaging with custom branding is available for export markets.
06

Documentation available includes WHO-GMP Certificate, DCGI Manufacturing Licence, CoPP, batch-wise CoA (sterility, particulate matter, pH, viscosity, assay), ICH Zone IVb stability data and CTD/ACTD dossiers on request. Note that CMC eye drops may be classified as a medical device in certain markets — our regulatory team can advise on the appropriate registration pathway.

CMC Lubricant Eye Drops Manufacturer in India