Allergy & CNS Syrup Manufacturer in India

WHO-GMP certified allergy and CNS syrup manufacturing — antihistamines, antiepileptics, sedatives and appetite stimulants — Cetirizine, Cyproheptadine, Promethazine and more — for domestic institutional supply and international export across 15+ countries.

Key Highlights

WHO-GMP Certified Facility
— Birkoni, Chhattisgarh
Sugar-Free and Paediatric
Formulations Available
DCGI Approved
Formulations
15+ Countries
Supplied

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About

Allergy & CNS syrup manufacturing at 9M India

9M India manufactures a comprehensive range of allergy and CNS (central nervous system) syrups and oral liquids at its WHO-GMP certified facility in Birkoni, Chhattisgarh. This category covers two clinically important areas: antihistamine and anti-allergic oral liquids for allergic rhinitis, urticaria and seasonal allergies — including Cetirizine syrup, Cyproheptadine syrup and Promethazine syrup — and CNS oral liquid formulations including antiepileptic syrups (Carbamazepine oral suspension, Levetiracetam oral solution, Phenobarbitone syrup) and sedative formulations. These are essential medicines with consistent institutional and retail demand across all 9M India’s export markets. Antihistamine syrups are particularly high-volume in the Middle East, Africa and South Asia where allergic disease prevalence is elevated, while antiepileptic oral liquids are critical for paediatric epilepsy management programmes globally.

Therapeutic sub-categories — Allergy & CNS Syrups

Our allergy & cns syrups range covers the following sub-categories and key molecules:

Sub-Category	Key Molecules & Formulations
2nd Generation Antihistamines	Cetirizine Hydrochloride Syrup 5mg/5ml — non-sedating antihistamine for allergic rhinitis, urticaria, allergic conjunctivitis
1st Generation Antihistamines	Promethazine Hydrochloride Syrup 5mg/5ml — sedating antihistamine, antiemetic, pre-anaesthetic. Chlorpheniramine Maleate syrup.
Appetite Stimulant / Antihistamine	Cyproheptadine Hydrochloride Syrup 2mg/5ml — antihistamine + antiserotonergic. Appetite stimulant, allergic conditions, migraine prophylaxis.
Antiepileptics	Phenobarbitone Syrup 20mg/5ml, Carbamazepine Oral Suspension, Levetiracetam Oral Solution — first and second-line antiepileptic oral liquids for paediatric epilepsy
Sedatives / Anxiolytics	Diazepam Oral Solution — benzodiazepine sedative and anxiolytic oral liquid
Combination Antihistamines	Promethazine + Paracetamol Syrup — antihistamine + antipyretic combination for cold and allergy with fever

Syrup and oral liquid manufacturing at 9M India

All syrups and oral liquid formulations at 9M India — including the allergy & cns syrups range — are manufactured under the following standards:

WHO-GMP certified liquid manufacturing facility
Automated syrup filling lines with in-process fill volume accuracy monitoring
Sugar-free formulations using approved sweeteners — Sorbitol, Sucralose, Saccharin
Amber glass and PET bottle formats — 30ml, 60ml, 100ml, 200ml
Child-resistant closures and dosing devices / measuring cups included
Dry syrup manufacturing under humidity-controlled environment
Multilingual labelling and serialisation for export markets
Stability studies — ICH Zone IVb (30°C/75% RH)

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Why 9M India

Why pharmaceutical buyers choose 9M India for allergy & CNS syrups

Cetirizine syrup — the most widely used non-sedating antihistamine oral liquid globally

Cetirizine Hydrochloride 5mg/5ml syrup is the standard second-generation antihistamine oral liquid for allergic rhinitis, chronic urticaria and allergic conjunctivitis in both adults and children. Unlike first-generation antihistamines, Cetirizine causes minimal sedation — making it preferred for daytime use. 9M India manufactures Cetirizine syrup for both retail and institutional supply with complete WHO-GMP documentation and sugar-free formulation option.
Cyproheptadine — dual antihistamine and appetite stimulant with high demand in African and ASEAN markets

Cyproheptadine 2mg/5ml syrup is a unique molecule combining antihistamine activity with antiserotonergic appetite-stimulating properties. It is widely used as an appetite stimulant in children — a high-volume indication in Africa and South Asia where paediatric undernutrition coexists with allergic conditions. 9M India manufactures Cyproheptadine syrup at scale for export to these markets with full GMP documentation.
Antiepileptic oral liquids — critical for paediatric epilepsy programmes

Antiepileptic syrups and oral solutions — Phenobarbitone, Carbamazepine and Levetiracetam — are essential medicines for paediatric epilepsy management. Children who cannot swallow tablets require oral liquid formulations, making these a consistent institutional demand item in hospital pharmacy and government paediatric neurology programmes. 9M India manufactures these specialty CNS oral liquids with complete documentation for export to institutional buyers.

Molecule Grid

Key allergy & CNS syrups formulations at 9M India

01

Cetirizine Hydrochloride Syrup 5mg/5ml | Antihistamine | 60ml / 100ml bottle | 2nd generation — non-sedating
02

Cyproheptadine Hydrochloride Syrup 2mg/5ml | Antihistamine + Appetite Stimulant | 100ml / 200ml bottle
03

Promethazine Hydrochloride Syrup 5mg/5ml | Antihistamine + Antiemetic + Sedative | 100ml bottle | 1st generation
04

Chlorpheniramine Maleate Syrup 2mg/5ml | Antihistamine | 60ml / 100ml bottle | 1st generation
05

Promethazine + Paracetamol Syrup | Antihistamine + Antipyretic combination | 60ml / 100ml bottle
06

Phenobarbitone Syrup 20mg/5ml | Antiepileptic | 100ml bottle | Paediatric epilepsy
07

Levetiracetam Oral Solution 100mg/ml | Antiepileptic | 300ml bottle | 2nd generation AED
08

Diazepam Oral Solution | Sedative / Anxiolytic | 100ml bottle | Benzodiazepine

Export Markets & Regulatory

Export markets & regulatory readiness

9M India exports allergy and CNS syrups to 15+ countries across Phase 1 markets including the UAE, Iraq, Egypt, Mexico, Russia, Kazakhstan, Sri Lanka and others in the Middle East, CIS, Africa and ASEAN. Antihistamine syrups are among the highest-volume oral liquid categories in retail pharmacy across all our active export markets. Antiepileptic oral liquids are essential institutional items in hospital paediatric departments globally.

WHO-GMP Certificate
DCGI Manufacturing Licence
Certificate of Pharmaceutical Product (CoPP)
Certificate of Analysis (CoA) — batch-wise
CTD / ACTD Dossier — on request
Stability Data — ICH Zone IVb (30°C/75% RH)

Partner with 9M India for allergy & cns syrups supply

Whether you are sourcing Cetirizine, Cyproheptadine, Promethazine or antiepileptic oral liquids — for institutional supply, government paediatric programmes or export distribution — 9M India delivers WHO-GMP certified manufacturing with complete documentation and reliable supply at scale.

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View All Syrup Categories

WHO-GMP
Certified
Sugar-Free
Options
DCGI
Approved
15+ Countries
Supplied

Submit An Enquiry

View All Syrup Categories

Therapeutic Categories

Syrup formulations across major therapeutic categories

We keep answer short

Frequently asked questions — allergy & cns syrups

01

Yes. 9M India manufactures Cetirizine Hydrochloride 5mg/5ml syrup at its WHO-GMP certified facility in Birkoni, Chhattisgarh. Cetirizine is a second-generation non-sedating antihistamine — the most widely prescribed antihistamine oral liquid globally for allergic rhinitis, urticaria and allergic conjunctivitis in adults and children from 2 years. Sugar-free formulation is available.
02

Cyproheptadine 2mg/5ml syrup is a first-generation antihistamine with unique antiserotonergic activity that stimulates appetite. It is widely used as an appetite stimulant for children with poor growth and undernutrition — a high-prevalence condition in Sub-Saharan Africa and South Asia. It is also used for allergic conditions, urticaria and migraine prophylaxis. 9M India manufactures Cyproheptadine syrup at scale for export to these high-demand markets.
03

Yes. 9M India manufactures Promethazine Hydrochloride 5mg/5ml syrup — a first-generation antihistamine with antiemetic, sedative and anticholinergic properties. Promethazine is widely used for allergic conditions, motion sickness, nausea and vomiting, pre-anaesthetic medication and as a sedative. It is a WHO Essential Medicine and one of the highest-volume antihistamine syrups in export markets.
04

Yes. 9M India manufactures antiepileptic oral liquid formulations including Phenobarbitone Syrup 20mg/5ml and Levetiracetam Oral Solution 100mg/ml for paediatric epilepsy management. These are essential medicines for children who cannot swallow tablets — a consistent institutional demand item in hospital paediatric neurology departments and government epilepsy programmes globally.
05

First-generation antihistamines (Promethazine, Chlorpheniramine, Cyproheptadine) cross the blood-brain barrier — causing sedation, which is a side effect in allergy treatment but a therapeutic benefit in nausea, pre-anaesthesia and sleep. Second-generation antihistamines (Cetirizine, Levocetirizine) do not significantly cross the blood-brain barrier — providing anti-allergic benefit without sedation. Both generations are in active export demand and 9M India manufactures syrup formulations across both classes.
06

Yes. Sugar-free antihistamine syrup formulations — using Sorbitol, Sucralose or Saccharin as sweeteners — are available for Cetirizine, Cyproheptadine and Chlorpheniramine. Sugar-free formulations are preferred for diabetic patients and in paediatric populations where sugar-containing syrups may contribute to dental caries. Please specify sugar-free requirement when placing an enquiry.
07

Documentation available includes WHO-GMP Certificate, DCGI Manufacturing Licence, Certificate of Pharmaceutical Product (CoPP), batch-wise Certificate of Analysis, ICH Zone IVb stability data and CTD/ACTD dossiers on request. For antiepileptic oral liquids classified as controlled or scheduled substances in certain markets, our regulatory team can advise on the appropriate export permit and documentation requirements.
08

Antihistamine syrup demand is highest in the Middle East, North Africa and South Asia — where allergic rhinitis and urticaria prevalence is elevated due to high dust and pollen burden, dry climatic conditions and increasing pollution levels. These are 9M India's primary Phase 1 export markets. Cyproheptadine appetite stimulant syrup shows particularly high demand in Sub-Saharan Africa where paediatric nutritional programmes drive significant volume.